THE T CLINIC

What Is Testosterone Replacement Therapy?

What is Testosterone Replacement Therapy?

Testosterone is one of the primary drivers of typically “masculine” characteristics in men. It is a sex hormone produced by the testes and results in characteristics such as sex drive, muscle mass and facial hair development. As we age blood testosterone levels drop from the age of 30 by 1-2% per year on average. This means our testosterone levels in our 50s may be up to 50% lower than it was in our 20s.

Testosterone Replacement Therapy (TRT) is a form of medical therapy in which clients use external testosterone to replace their deficiency in the hormone. The purpose of TRT is to restore serum testosterone to healthy levels within natural norms. Studies seem to indicate this can somewhat ‘rewind the clock’, restoring vitality and athleticism to peak levels.

How does testosterone change with age?

As we age, a gradual and often unnoticed decline in testosterone levels will occur. This natural process typically starts in the late 20s to early 30s, with levels falling by approximately 1-2% each year. While the drop is subtle at first, its effects can accumulate, leading to noticeable changes in how a man feels, performs, and lives.

Because these symptoms often appear gradually, they’re sometimes dismissed as inevitable signs of aging. But low testosterone is a medical condition — not just “getting older.” Identifying the cause through a simple blood test can be the first step to restoring balance, performance, and confidence.

How does TRT help?

Testosterone Replacement Therapy (TRT) involves the administration of bioidentical testosterone — typically through topical gels, tablets, or injectable formulations — to restore hormone levels in men with clinically low testosterone.

The aim of TRT is not to exceed natural limits, but to bring your testosterone levels back into the optimal range commonly seen in your 20s and 30s. By doing so, we address the wide range of symptoms associated with testosterone deficiency, including fatigue, low mood, reduced muscle mass, poor concentration, and diminished libido.

Importantly, TRT differs from the use of anabolic steroids, which are often misused to elevate testosterone to supraphysiological levels for performance enhancement. At Karma Health, our approach is medically supervised, evidence-based, and focused on long-term wellbeing.

When prescribed and monitored appropriately, TRT can raise testosterone levels by up to 200%, leading to meaningful improvements in both physical and mental health.

Other factors affecting testosterone

Blood testosterone levels reduce as we age, therefore it is common for men over 40 to suffer with low testosterone levels. The American Urology Association estimate that up to 50% of all men may have symptoms of low testosterone. In addition to age, several other factors may contribute to low testosterone levels, these include:

– High body fat levels
– Previous anabolic steroid use
– Chronic pain patients, such as those taking opiates
– Patients with chronic health conditions such as diabetes, lung disease or kidney disease
– Chronic Stress
– Excessive Alcohol Consumption
– Patients on antidepressants
– Previous cancer patients
– Inherited medical conditions

What are the symptoms of testosterone deficiency?

Testosterone is a crucial hormone responsible for various functions, including maintaining muscle mass, bone density, mood stability, and sexual health. As men age, it’s natural for testosterone levels to decline. However, some individuals experience a more significant decrease, leading to symptoms such as:

– Reduced energy levels
– Decreased libido
– Mood disturbances
– Loss of muscle mass
– Increased body fat

Developed with the highest standards.

Our clinic was developed in conjunction with the clinicians at the world-renowned Harley Street TRT clinic. As such, the Karma Health team have been trained to the same rigorous standards as those at Harley Street TRT and work alongside these clinicians to provide you with the highest standard of care.

BASE

Our entry-level Testosterone Replacement Therapy plan, this plan provides only the TRT essentials for you to feel revitalised.

£120

T Clinic Base

THRIVE.

Our mid-level Tesosterone Replacement Therapy Plan, the THRIVE builds on the BASE plan with regular blood testing included to ensure long term health.

From £150/month

T CLINIC THRIVE.

ASCEND.

The ASCEND plan is the most comprehensive TRT plan available. It provides effective testosterone replacement therapy to allow you to live better and further. This plan also includes more comprehensive health testing to ensure continued long-term health as you continue along your TRT journey.

From £250/month

T CLINIC: ASCEND

Your Testosterone Replacement Therapy Journey

Initial Blood Test

We recommend that all prospective clients begin with an initial blood test* to determine whether low testosterone may be contributing to their symptoms.

Primary Consultation

Once your blood testosterone results are available, we recommend booking an initial consultation with one of our experienced TRT clinicians. During this appointment, a thorough medical history and physical examination will be conducted. We will also discuss your results in detail, explore suitable treatment options, and provide comprehensive information about Testosterone Replacement Therapy.

Follow-Up Consultation

Once you have completed your primary consultation, you will then have a follow-up consultation in which you will select your TRT plan and will commence your chosen therapy.

Regular Monitoring

We believe in safe and evidence-based therapy, as such we provide regular blood testing and medical consultations as standard with our plans. Every 4 months you will have medical assessments either in-person or via online consultation.

Why Karma?

Face-to-face Consultations

We offer online consultations for our remote clients and in-person reviews for those who would prefer a more hands-on approach.

Care centered around you.

We place you at the center of everything we do. From stay at home mums to world renowned athletes, we understand our clients live busy lives. As such, our client relation team works with you to ensure regular health testing fits within your schedule.

World-class testing

From heritage facilities to Artifical Intelligence led testing, Karma provides the most advanced health testing in the North West.

Bespoke wellness

Each wellness plan is personalised by our expertly-trained clinicians, using analysis from all aspects of your health, including family and past medical history, and social health.

THE T CLINIC

What Is Testosterone Replacement Therapy?